Amanda Knox's debut Edinburgh Fringe show, Cartwheel, has received mixed reviews from critics, who have broadly agreed that it is "sincere" but not effective as stand-up comedy. Knox, who was convicted and later acquitted of murdering British student Meredith Kercher in Italy in 2007, arrived at the festival with one of this year's most talked-about productions, and the show drew criticism from Kercher's sister even before it opened.

Critics were split on quality, with The Guardian awarding four stars and praising its "spirit of defiance", while The Times and The Daily Telegraph each gave two stars, describing it as "stilted" and lacking comic timing. Several reviewers, including Broadway World with three stars, agreed the show works better as a personal, one-woman piece about motherhood and trauma than as conventional comedy, noting it respectfully avoids making light of Kercher's death. Knox, now a mother, has said the show is about how she might one day explain the case to her daughter, having previously written two books and produced a biographical drama about her experience.