# College football Week 10 predictions: Best bets, picks against the spread

- URL: https://talkfuse.com/story/college-football-week-10-predictions-best-bets-picks-against-the-spread/
- Published: 2026-11-06T17:00:00+00:00
- Updated: 2026-11-06T17:40:44+00:00
- Original publisher: New York Post (publisher lean: Right)
- Original article: https://nypost.com/2026/11/06/betting/college-football-week-10-predictions-best-bets-picks-against-the-spread/
- Topics: Football, Sport, World

## Key points

- Notre Dame’s game against Miami could reshape its playoff prospects.
- The article picks the Irish to cover a 6.5-point spread.
- It offers against-the-spread picks for several other Week 10 games.

## Summary

The article sets out betting predictions and picks against the spread for several college football games in Week 10. It highlights Notre Dame’s home match against top-ranked Miami as especially important: a win could strengthen the Irish’s playoff case after the committee placed them 11th, while a loss could leave them on the edge of qualification.

The article backs Notre Dame to cover a 6.5-point spread, citing quarterback CJ Carr’s 18 touchdown passes and one interception, and Miami’s 128th-ranked pass defence. Other picks include Virginia Tech, Illinois, Utah, Minnesota, Texas, South Carolina and Ohio State; the text also favours LSU against Alabama. It notes that Utah has faced the fourth-easiest schedule among power conference teams and that South Carolina quarterback LaNorris Sellers has rushed for 192 yards and four touchdowns over his past two games.

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Summarised by TalkFuse (https://talkfuse.com/). Quote the original publisher for the reporting and link this page for the summary and discussion.