The costume designer for Season 3 of 'Interview with the Vampire' reimagined the visual approach by prioritizing vivid colors and varied textures instead of the traditional red and black typically associated with vampires. This aesthetic shift reflects Lestat's evolution into a rockstar character and his increasingly manic personality. The designer drew inspiration from iconic musicians including Iggy Pop, David Bowie, and Freddie Mercury, while deliberately avoiding direct modeling of any single performer to allow Lestat's character to maintain his own distinct visual identity.

The production took a labor-intensive approach, with roughly three-quarters of the costumes being handcrafted to achieve the intended visual design. Symbolic fabric choices were employed, such as silk incorporated into both Lestat and his mother's garments to maintain thematic connections to their 18th-century origins, with the designer hinting at additional Easter eggs within these textile selections. Louis's wardrobe underwent a similar redesign to visually communicate his liberation through expanded use of color and pattern, though the designer faced constraints in sourcing materials befitting his character's extreme wealth within typical television production budgets.