Damon Wayans Reunites With ‘In Living Color’ Co-Star David Alan Grier in ‘St. Denis Medical’ Season 3 Premiere

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Damon Wayans Reunites With ‘In Living Color’ Co-Star David Alan Grier in ‘St. Denis Medical’ Season 3 Premiere

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Variety · 3 hours ago

Damon Wayans will reunite on screen with his former "In Living Color" co-star David Alan Grier when he guest stars in the Season 3 premiere of NBC's "St. Denis Medical," airing on 2 November. Wayans plays Dr Highland, a charming but pompous doctor filling in at the fictional hospital while Grier's regular character, Ron, recovers from surgery, with staff and patients quickly won over by his bedside manner. The pairing revives a comic partnership dating back over three decades, giving the workplace mockumentary a notable guest-star boost heading into its new season.

"St. Denis Medical" follows staff at an underfunded, understaffed Oregon hospital and is led by Allison Tolman, with Grier as the gruff emergency physician Ron. Grier appeared in all five seasons of "In Living Color" (1990–1994), while Wayans starred in its first three seasons and returned for guest spots in Season 4. Wayans is also known for ABC's "My Wife and Kids" (2001–2005) and Fox's "Lethal Weapon" (2016–2019); the series is created by Justin Spitzer and Eric Ledgin for Universal Television.

  • Damon Wayans guest stars in "St. Denis Medical" Season 3 premiere, out 2 November.
  • He reunites with "In Living Color" co-star David Alan Grier.
  • Wayans plays a doctor covering for Grier's character during his recovery.

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Damon Wayans and David Alan Grier first became known together as members of the original cast of "In Living Color," a sketch comedy show that ran from 1990 to 1994 and helped launch both their careers. Wayans appeared in the show's first three seasons before moving on to other projects, including the sitcom "My Wife and Kids" and the action series "Lethal Weapon," while Grier stayed for the full run.

"St. Denis Medical" is a mockumentary-style comedy on NBC set in a struggling, short-staffed hospital in Oregon. It stars Allison Tolman as part of an ensemble cast, with Grier playing Ron, a bad-tempered emergency room doctor who is one of the show's regular characters. The series began in 2024 and is now heading into its third season.

The two actors' guest-star reunion matters mainly to fans of "In Living Color," as it brings back a comic pairing not seen together on screen in this way for more than thirty years, and gives "St. Denis Medical" a well-known face to help draw attention to its new season.

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