Did Ohio State snap Indiana’s 22-game winning streak?

Yes. Ohio State beat Indiana 19–15, ending the Hoosiers’ 22-game winning streak and handing them their first loss since December 2024 [1].

Sources

Ohio State snaps Indiana’s 22-game winning streak, hands reigning champs first loss since 2024 in thriller — Fox News
The Cignetti effect is real: Indiana football sparks an unbelievable ‘revival’ in Bloomington — Fox News

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