Bethesda has announced that Obsidian Entertainment will develop a new entry in the Fallout universe, rekindling a partnership that last produced Fallout: New Vegas in 2010. The project is positioned as distinct from the mainline Fallout 5, which remains in preproduction. Todd Howard expressed enthusiasm for the collaboration, stating that timing favours the undertaking and that Bethesda's franchise leadership will oversee the initiative.

According to reporting from Bloomberg, Microsoft cancelled development of an Avowed sequel to clear resources for this Fallout title. Bethesda has committed to sharing additional details about the game's scope and direction at a future date, though Howard declined to elaborate on specific gameplay elements or narrative direction during the initial announcement.