Coyote vs. Acme, an animated and live-action hybrid Looney Tunes film, has become a box office success story that vindicates audiences' faith in the project. The film's continued strong performance demonstrates that Warner Bros.' decision to shelve it as a tax write-off was premature, with the studio's lack of confidence in the picture now appearing as a significant misjudgement.

The film has earned over £80 million worldwide (approximately £55 million domestically) and has now surpassed five other Warner Bros. 2026 releases, including Practical Magic 2, The Mummy, Evil Dead Burn, The End of Oak Street, and They Will Kill You. After the backlash to its original shelving, distribution rights were acquired by Ketchup Entertainment for £50 million, allowing the film to reach audiences despite the studio's initial mishandling of its commercial prospects.