Cryogenic Coolant in Palworld is a crafted resource needed for powerful cold-resistant equipment and several advanced items, including weapons, saddles and tools. This makes it important for players preparing to explore harsh regions such as Mount Obsidian and Feybreak Island, but it cannot be collected directly in the world.

The recipe unlocks at level 31 and must be made at a Production Assembly Line, unlocked at level 29. It uses Pal Fluids and Ice Organs, obtained from water- and ice-type Pals; building the assembly line requires 100 Ingots, 10 Cement, five Wooden Boards and 20 Nails. Coolant is used in items ranging from the level-33 Water Grenade to level-77 Cold-Resistant Ancient Armour.