UK trial to test ADHD and diabetes drugs in 1,200 people with Alzheimer’s

Daily Mail ·

A UK trial will test existing medicines, including the ADHD drug atomoxetine, to see whether they can ease symptoms or slow processes linked to Alzheimer’s disease. Its multi-drug design aims to speed up treatment research, which matters because current trials can take many years to show whether a medicine works.

The Ad-Smart trial will start with atomoxetine and the type 2 diabetes drug metformin, comparing them with a shared placebo group. It aims to recruit 1,200 people across up to 20 NHS sites over the next 18 months, with initial results expected by 2030; researchers will track participants using regular scans and blood tests. Alzheimer’s affects around 600,000 people in the UK.

In short

  • UK researchers will test atomoxetine and metformin in Alzheimer’s patients.
  • Ad-Smart aims to recruit 1,200 people at up to 20 NHS sites.
  • Researchers hope the trial design will speed up treatment testing.

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Originally published by Daily Mail as “Hundreds of Alzheimer’s patients to get ADHD drugs in world-leading trial – studies suggest pills could tackle dementia symptoms”.

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