Karla Souza To Star In ‘Grey’s Anatomy’ Texas Spinoff

Karla Souza has been cast as the lead in ABC’s new Grey’s Anatomy spin-off, set at a rural medical centre in West Texas. The series is described as an edgy drama about a team providing care in an isolated area, and marks the franchise’s first production to film outside Los Angeles.

Souza will play Carolina “Lina” Hall, a haunted, cynical doctor in her 40s who runs the centre. The untitled series is being developed by Grey’s Anatomy creator Shonda Rhimes and current showrunner Meg Marinis, with Betsy Beers and Ellen Pompeo among its executive producers. It is in pre-production in Albuquerque, New Mexico, after failing to secure a California tax credit; filming is expected to start around February or March 2027, ahead of a planned premiere in the 2027–28 season.