Pushsquare has reviewed Mewgenics for PS5, a cat-breeding, turn-based roguelike strategy game created by Edmund McMillen (The Binding of Isaac) and Tyler Glaiel (The End Is Nigh). Despite being made by just two developers, the reviewer considers it a strong contender for game of the year and calls it the best roguelike since The Binding of Isaac, praising its depth, polish and originality within the crowded roguelike genre.

The game offers over 100 hours of content built around breeding or rescuing stray cats with inheritable stats, mutations and diseases, then assigning them classes and equipment for runs through areas such as sewers, caves and deserts. Combat takes place on a 12×12 grid featuring dynamic weather and environmental effects, such as spreading fire or dodge-boosting grass, alongside deep ability systems that unlock as cats level up. The reviewer highlights its charming presentation, cross-save functionality and jazz soundtrack, with only crude humour, questionable themes and minor UI issues noted as drawbacks.