Ryan Murphy has revealed that Ariana Grande was originally set to appear in American Horror Story season 13 in a crossover between the show and his earlier series Scream Queens, where Grande would have reprised her role as Chanel #2. The appearance did not materialise due to Grande's touring schedule for her Eternal Sunshine Tour, though Murphy has indicated he remains keen on the idea and has not ruled out attempting it in future. This revelation highlights the ongoing scheduling challenges that can affect high-profile television projects, even when the parties involved are enthusiastic about participation.

Murphy noted that Grande was upfront about the difficulty of coordinating her tour dates with production, and he has postponed rather than abandoned the crossover concept. Beyond this season, Murphy has suggested he is open to reviving Scream Queens entirely, with multiple cast members expressing interest in returning: Emma Roberts, Billie Lourd, Lea Michele, Ariana Grande and Glen Powell have all reportedly indicated willingness to participate. Co-creator Ian Brennan reflected that the show's cancellation after two seasons was partly a consequence of its timing during the transition from network to streaming television, noting that its ratings would now be considered valuable by modern standards.